Author

Simon Manuel Tria

QIMR Berghofer Medical Research InstituteORCID 0000-0002-0562-7916Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:diffusion model· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexandra M. KaneiD· 1 shared Amanda Louise BainiD· 1 shared Antonella PapaiD· 1 shared Asmerom Tesfamariam SengaliD· 1 shared B. Bowden· 1 shared Barbara LeggettiD· 1 shared Behnam RashidiehiD· 1 shared Ben B. Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alexandra M. KaneORCID

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2 papers

Recent·Most cited

Cancer BiologyAdvanced SciencePeer-reviewedAug 10, 2026

Genetic Ablation and Multi-Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain…·Kum Kum Khanna

This study shows that CEP55 promotes tumorigenesis in cancer models and its deletion suppresses tumor growth and improves survival, especially in PTEN-deficient cancers.

DOI 10.1002/advs.76782

mouseproteomics

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Cancer BiologyBritish Journal of CancerPeer-reviewedFeb 23, 2026

Attenuation of the CpG Island Methylator Phenotype and lack of WNT signaling activation restrains Kras mutant intestinal neoplasia

Lochlan Fennell, Cheng Liu, Alexandra M. Kane…·Vicki Whitehall

This study compares Kras and Braf mutant intestinal neoplasia in mice, showing Kras mutations lead to less aggressive serrated lesions with reduced WNT signaling activation and attenuated DNA methylation changes compared to Braf mutations.

1 citation

mouseDNA methylation

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