Leyuan Ma

This paper introduces an mRNA-LNP method to assess immune effector cell-mediated cytotoxicity, showing it is rapid, consistent, and compatible with diverse tumor models.

This paper improves lentiviral gene delivery to mammalian cells by engineering virus-envelope and cell-surface interactions using FITC labeling and chimeric envelopes.

This study investigates how spike structures on virus-like nanoparticles enhance immune responses in macrophages through proteomic analysis of signaling pathways.

This study develops a method to generate optimized peptide ligands for CAR-T cell restimulation, demonstrating enhanced expansion and memory development in preclinical models.

This study shows ammonia reduces NK cell antitumor activity by decreasing mature perforin levels in the tumor microenvironment.