Author

Darci Jones Trader

University of California SystemORCID 0000-0002-0607-1243Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Carlos Bandeira DuarteiD· 1 shared Cody A. LoyiD· 1 shared Eslam M.H. AliiD· 1 shared Ivan L. SalazariD· 1 shared Kate A. Kragness· 1 shared Lauren Veronica AlbrechtiD· 1 shared Laurence J. SeabrookiD· 1 shared Margarida V. CaldeiraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Carlos Bandeira DuarteORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedApr 19, 2025

ByeTAC: Bypassing an E3 Ligase for Targeted Protein Degradation

Cody A. Loy, Eslam M.H. Ali, Laurence J. Seabrook…·Darci Jones Trader

This paper introduces ByeTACs, bifunctional degraders that target proteins by interacting with the 26S proteasome instead of an E3 ligase, and shows they effectively degrade BRD4.

43 citationstop 1%

experimental assaydrug response / drug discovery

𝕏 PostBluesky

NeuroscienceAPOPTOSISPeer-reviewedMar 17, 2025

Activation of the 20S proteasome core particle prevents cell death induced by oxygen- and glucose deprivation in cultured cortical neurons

Ivan L. Salazar, Michele Curcio, Miranda Mele…·Carlos Bandeira Duarte

This study shows that activating the 20S proteasome core particle prevents cell death in cortical neurons under oxygen- and glucose-deprivation conditions.

2 citations

ratexperimental assay

𝕏 PostBluesky