Seok‐Yong Lee

This study presents cryo-EM structures and functional analyses of TRPM8 activation by cold and menthol, revealing mechanisms of cold sensing and menthol specificity.

This study determines the cryo-EM structures of URAT1 with inhibitors and reveals their binding mechanisms and conformational changes.

The paper presents the cryo-EM structure of the FtsEX-EnvC complex from V. cholerae and shows how EnvC's conformational changes regulate amidase activity for septal peptidoglycan hydrolysis.

This study reports crystal structures of MurJ in different conformations to elucidate its mechanism of lipid flipping and identify a key ion for function.