Yang Suo

This study determines the cryo-EM structures of URAT1 with inhibitors and reveals their binding mechanisms and conformational changes.

The paper presents the cryo-EM structure of the FtsEX-EnvC complex from V. cholerae and shows how EnvC's conformational changes regulate amidase activity for septal peptidoglycan hydrolysis.

The paper describes a scaffold system using E. coli inner membrane to cluster enzymes in fatty acid synthesis II pathway, enhancing metabolism flux and product exportation.