Maria Czyzyk-Krzeska

This study shows that SLC25A3-mediated copper transport to mitochondria is essential for skeletal myoblast differentiation and survival of mature myotubes.

This study uses SEC-ICP-MS to assess copper allocation to cytochrome c oxidase and identifies key transporters involved in mitochondrial copper trafficking.

This study identifies PRPS2 as a key regulator of redox homeostasis in Myc-driven lymphomas, showing that its inactivation causes reductive stress and cell death.

This study shows copper drives metabolic remodeling and progression in clear cell renal cell carcinoma by coordinating bioenergy, biosynthesis, and redox homeostasis.

This paper introduces ceSAR, a method combining docking and transcriptional signature connectivity to improve drug discovery and repurposing by reducing false positives and computational costs.