Author

Tim Beaumont

Amsterdam UMC Location University of AmsterdamORCID 0000-0002-0778-8027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Marit J. van GilsiD· 3 shared Rogier W. SandersiD· 3 shared Andrew B. WardiD· 2 shared Denise GuerraiD· 2 shared Andreas Chrysostomou· 1 shared Gius KersteriD· 1 shared Godelieve J. de BreeiD· 1 shared Hailee R. PerrettiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Marit J. van GilsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 30, 2025

A dynamic activation-memory cycle organizes the human IgG⁺ memory B cell compartment

Laura T. M. Graus, Andreas Chrysostomou, Denise Guerra…·Mathieu A. F. Claireaux

This study defines the dynamic activation-memory cycle of human IgG memory B cells through single-cell profiling, revealing distinct reactivation trajectories and functional roles in humoral immunity.

DOI 10.1101/2025.10.30.685644

humanscRNA-seq

𝕏 PostBluesky

ImmunologyCell ReportsPeer-reviewedSep 1, 2024

Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses

Philip J. M. Brouwer, Hailee R. Perrett, Tim Beaumont…·Andrew B. Ward

This study identifies neutralizing antibody epitopes against Lassa virus GPC using electron microscopy, revealing challenges in vaccine-induced responses and opportunities for improved vaccine design.

10 citations

protein structureexperimental assay

𝕏 PostBluesky

MicrobiologyHuman Vaccines & ImmunotherapeuticsPeer-reviewedAug 20, 2024

Broadening sarbecovirus neutralization with bispecific antibodies combining distinct conserved targets on the receptor binding domain

Denise Guerra, Laura Radić, Mitch Brinkkemper…·Tim Beaumont

This study develops bispecific antibodies that target conserved regions on the SARS-CoV-2 spike protein, showing improved neutralization breadth against multiple sarbecovirus strains.

3 citations

experimental assayhost-pathogen & immune response

𝕏 PostBluesky