Author
Amsterdam University Medical CentersORCID 0000-0002-5852-5833Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Tom G. Caniels, Madhu S. Prabhakaran, Sashank Agrawal…·Rogier W. Sanders
This study shows that sequential vaccination can mature VRC01-class B cells into antibodies that neutralize a broad range of HIV-1 viruses.
Jade Jansen, Killian E. Vlaming, Leanne C. Helgers…·Neeltje A. Kootstra
This study shows that SMNP, a TLR4-targeted adjuvant, induces stronger immune activation and reduces HIV-1 reservoir size in PWH ex vivo compared to MPLA.
Sem Tamara, Danique M.H. van Rijswijck, Jacqueline van Rijswijk…·Maurits A. den Boer
The paper introduces AbDirect, a proteomics-based method for antibody discovery that identifies potent neutralizing antibodies missed by single-cell BCR sequencing in COVID-19 plasma.
Laura T. M. Graus, Andreas Chrysostomou, Denise Guerra…·Mathieu A. F. Claireaux
This study defines the dynamic activation-memory cycle of human IgG memory B cells through single-cell profiling, revealing distinct reactivation trajectories and functional roles in humoral immunity.
Pien M van Paassen, Alexander O. Pasternak, Dita C. Bolluyt…·Godelieve J. de Bree
Mathieu A. F. Claireaux, George Elias, Gius Kerster…·S. Marieke van Ham
The paper identifies novel stages in IgG memory B cell and antibody-secreting cell differentiation by analyzing antigen-specific B cells from different pathogens using high-dimensional flow cytometry.