Molecular BiologybioRxivPreprint
Oligomerization-driven MLKL ubiquitylation antagonises necroptosis
Zikou Liu, Laura F. Dagley, Kristy Shield‐Artin…·John Silke
This study demonstrates that MLKL ubiquitylation, triggered by oligomerization, regulates necroptosis by modulating MLKL activity and turnover.