Sophia J. Weber

This study uses calcium and dopamine sensors to examine nucleus accumbens activity during food seeking and extinction-reinstatement paradigms, finding changes in both signals during training and reinstatement.

This study shows that heroin relapse triggered by drug cues persists for over a year in abstinent rats, indicating long-term vulnerability to opioid relapse.

The paper shows that distinct prelimbic cortex ensembles encode response execution and inhibition during different phases of operant learning in rats.

This study investigates the role of dopamine transmission at D1 and D2 receptors in the nucleus accumbens in incubated cocaine craving, finding that DA contributes to craving after incubation through postsynaptic changes.

The paper develops improved GRABDA sensors to monitor dopaminergic activity in vivo, showing high sensitivity and spatially resolved DA release in mice during behaviors.

The paper establishes a mouse model of incubation of palatable food craving and identifies brain-wide activation patterns using whole-brain activity mapping.

SMART is an open-source R package that extends WholeBrain for registering and segmenting intact mouse brain images to the Allen Brain Institute CCF, with a modified iDISCO+ protocol for Fos labeling.

This study investigates DS-controlled incubation of cocaine craving in rats, finding that cocaine-seeking behavior increases over abstinence, unlike food-seeking behavior.