Maximilian AH Jakobs

The paper investigates how mutations in the FUS protein affect axonal cytoskeletal organisation in ALS/FTD models, finding reduced actin density and axonal branch complexity.

The paper identifies a molecular mechanism by which Patronin amplifies fusome asymmetry to select the oocyte in the female germline cyst.

The paper shows that receptor-ribosome coupling enables selective mRNA translation in axons in response to guidance cues, with receptor-specific interactomes mediating this process.