Molecular BiologybioRxivPreprint
Identification of translation events that drive nonsense-mediated mRNA decay reveals functional roles for noncoding RNAs
1 citation
Author
David J. Young
National Institutes of HealthORCID 0000-0002-0885-8568Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2025 · peak 1/yrCo-Author Collaboration Network
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- BioengineeringMolecular TherapyPeer-reviewed
In vivo tracking of ex vivo generated 89Zr-oxine labeled plasma cells by PET in a non-human primate model
David J. Young, Abigail J Edwards, Kevin G Quiroz Caceda…·Cynthia E. Dunbar
The paper demonstrates a method to track ex vivo generated B cells in non-human primates using PET imaging, showing stable distribution and feasibility of repeated infusions.
13 citations - Molecular BiologybioRxivPreprint
Validation and Long-Term Follow Up of CD33 Off-Targets Predicted In Vitro and In Silico Using Error-Corrected Sequencing in Rhesus Macaques
Aisha A. Aljanahi, Cícera Regina Lazzarotto, Shirley Chen…·Cynthia E. Dunbar
The paper validates off-target effects of CRISPR/Cas9 in rhesus macaques using error-corrected sequencing, showing that in vitro and in silico methods have limited predictive accuracy.
1 citation