Author

Aisha A. Aljanahi

National Institutes of HealthORCID 0000-0002-2345-5070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cynthia E. DunbariD· 2 shared Tae–Hoon ShiniD· 2 shared Yifan ZhouiD· 2 shared Ashley Laurel Gin· 1 shared Bradley S. Toms· 1 shared Byung‐Chul LeeiD· 1 shared Byung‐Chul LeeiD· 1 shared Chuanfeng WuiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Cynthia E. DunbarORCID

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2 papers

Recent·Most cited

Cell BiologyCell stem cellPeer-reviewedMar 19, 2024

Impact of CRISPR/HDR-editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques

Byung‐Chul Lee, Ashley Laurel Gin, Chuanfeng Wu…·Cynthia E. Dunbar

This study compares CRISPR/HDR and lentiviral transduction effects on HSPC engraftment and clonal dynamics in rhesus macaques, finding HDR-edited cells decline rapidly while lentiviral cells persist longer.

31 citations

ratexperimental assay

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Molecular BiologybioRxivPreprintJul 5, 2020

Validation and Long-Term Follow Up of CD33 Off-Targets Predicted In Vitro and In Silico Using Error-Corrected Sequencing in Rhesus Macaques

Aisha A. Aljanahi, Cícera Regina Lazzarotto, Shirley Chen…·Cynthia E. Dunbar

The paper validates off-target effects of CRISPR/Cas9 in rhesus macaques using error-corrected sequencing, showing that in vitro and in silico methods have limited predictive accuracy.

1 citation

ratwhole-genome sequencing

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