Yanik Weber

This paper demonstrates transient prime editor expression in mice to correct a genetic liver disease, reducing blood phenylalanine levels below the therapeutic threshold.

This paper develops a DNA aptamer biosensor to enable high-throughput screening of tryptophan synthase variants in droplets, identifying 5-fold improved enzymes.

This study uses prime editing in mice brains to introduce a mutation in the Adrb1 gene, leading to increased activity and exploratory behavior.

This paper improves the light sensitivity of Magnets photosensors through directed evolution, enabling tunable optogenetic regulation in bacteria and mammalian cells.