Benjamin D. Engel

This study identifies three photoprotective mechanisms in diatoms under light stress: detachment of oxygen-evolving complex proteins, NPQ in the antenna, and energy spillover between photosystems.

This study shows that far-red light induces structural changes in cyanobacterial thylakoids, reorganizing antenna-photosystem complexes and revealing persistent membrane heterogeneity.

MemBrain v2 couples a generalist U-Net cryo-ET membrane segmenter, a mesh-based picker reaching 91% F1 for photosystem II from one annotated membrane, and geodesic particle statistics.

This study shows that the lateral distribution of cytochrome b6f in thylakoid membranes affects photosynthetic electron transfer efficiency in Chlamydomonas reinhardtii.

The paper determines the structure of chlororibosomes in Chlamydomonas reinhardtii, revealing an additional arm domain on the small subunit composed of chloroplast-encoded extensions.

This study characterizes the pyrenoid structure and molecular components of Chlorella sorokiniana, revealing conserved inorganic carbon delivery machinery and novel proteins involved in pyrenoid assembly and starch tethering.

Stoic predicts protein complex stoichiometry using protein language model embeddings and graph neural networks, achieving fast and accurate results for homomeric and heteromeric complexes.

The paper examines changes in chloroplast ribosomes during evolution from cyanobacteria to land plants, identifying structural features and protein modifications.

The paper identifies RBMP2 as essential for forming the reticulated membrane region in the algal pyrenoid, which is critical for CO2 delivery and growth.

The paper shows that mature Arabidopsis thylakoid membranes can reversibly transition from lamellar to gyroid cubic structures without losing photosystem II function.

This study reveals how BCRII enzymes use electron-bifurcation modules to reduce aromatic rings beyond typical biological redox limits.

This study provides a molecular and structural map of the ciliary base in mammalian multiciliated cells using advanced imaging and molecular techniques.

The paper introduces an Advanced Mobile Laboratory (AML) for field-based microbial ecology and cell biology, enabling multiscale analysis of environmental samples directly at the sampling site.

This study shows that varying the number of binding motifs in a disordered protein affects pyrenoid assembly and algal fitness.

Automated cryogenic plasma-focused ion beam milling and cryo-electron tomography of Chlamydomonas reinhardtii yield 1,829 annotated cellular tomograms and sub-nanometer in situ structures of six macromolecular complexes.

This study identifies C2CD3 as a radial organizer of the distal centriole and appendages, revealing its role in structuring the luminal ring and interacting with the DISCO complex.

Icecream improves cryo-ET reconstruction by addressing denoising, missing-wedge recovery, and computational efficiency using equivariant deep learning.

The paper uses cryo-electron tomography to visualize mitochondrial respiratory complexes in Chlamydomonas reinhardtii, revealing their organization into distinct membrane domains and a respirasome structure with cytochrome c binding.

This study uses cryo-ET and AI-based methods to analyze thylakoid membrane organization in spinach chloroplasts, revealing similarities to green algae despite differences in 3D architecture.

The paper identifies a protein interaction network in the diatom pyrenoid, revealing a structural shell critical for CO2 fixation and suggesting convergent evolution with prokaryotic carboxysomes.

This study identifies a protein shell surrounding diatom pyrenoids that enhances CO2 fixation efficiency and reveals its structural and functional role through in vivo and in vitro analyses.

Surforama enables interactive visualization and analysis of membrane proteins in cryo-ET data by rendering local densities on segmented surfaces and exporting results for further analysis.

MemBrain detects membrane proteins in cryo-ET data using a deep learning pipeline, achieving high accuracy with minimal labels and generalizing across different cell types and imaging methods.

This paper introduces DeepFinder, a deep learning method that improves macromolecule identification in 3D cellular cryo-ET data by localizing multiple species with high accuracy.

This study characterizes the mitoribosome structure and function in Chlamydomonas reinhardtii, revealing its unique RNA assembly, protein components, and membrane attachment mechanisms.

This study identifies the structural basis of Rubisco phase separation in the pyrenoid by analyzing interactions between Rubisco and its linker protein EPYC1 in Chlamydomonas reinhardtii.