Author

Lena Rauch‐Wirth

University Hospital UlmORCID 0000-0002-0952-3559Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Andrea ImleiD· 1 shared Frederik GrawiD· 1 shared Jan MünchiD· 1 shared Katrin Wuebben· 1 shared Liv ZimmermanniD· 1 shared Nadine Tibroni· 1 shared Oliver T. FackleriD· 1 shared Petr ChlandaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Andrea ImleORCID

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1 paper

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedMay 9, 2026

A tissue-intrinsic mechanism sensitizes HIV-1 particles for TLR-triggered innate immune responses

Samy Sid Ahmed, Liv Zimmermann, Andrea Imle…·Oliver T. Fackler

The paper identifies a tissue-intrinsic mechanism where the extracellular matrix restricts HIV-1 infectivity and enhances innate immune detection through conformational changes in viral Env and TLR recognition.

DOI 10.1038/s41467-026-72586-3

humanexperimental assay

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