Author

Alicia M. McConnell

Boston Children's HospitalORCID 0000-0002-0984-4045Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Assay:bulk RNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Leonard Ira ZoniD· 3 shared Chloé S. BaroniD· 2 shared A. S. LengyeliD· 1 shared Aikaterini DedeiliaiD· 1 shared Akinori KawakamiiD· 1 shared Alexander Andreas NavariniiD· 1 shared Alexandra I.T. Lakatos· 1 shared Alina MuelleriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

Leonard Ira ZonORCID

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3 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedJul 22, 2025

Specific oncogene activation of the cell of origin in mucosal melanoma

Swathy Babu, Jiajia Chen, Chloé S. Baron…·Megan L. Insco

This study develops a zebrafish model of mucosal melanoma by activating an oncogene and inactivating tumor suppressors, revealing that internal melanocytes give rise to tumors with distinct transcriptional and chromatin features.

6 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintOct 22, 2024

BMP-dependent oligoclonal cancer attractor state precedes neural crest fate in melanoma initiation

Alicia M. McConnell, Maggie H. Chassé, Haley R. Noonan…·Leonard Ira Zon

The paper identifies a BMP-dependent attractor state in melanoma precursor cells that precedes neural crest fate and is associated with ID1 expression in human melanoma.

1 citation

zebrafishscRNA-seq

𝕏 PostBluesky

Cancer BiologyScientific ReportsPeer-reviewedSep 14, 2024

MITF regulates IDH1 and NNT and drives a transcriptional program protecting cutaneous melanoma from reactive oxygen species

Elisabeth Roider, Alexandra I.T. Lakatos, Alicia M. McConnell…·David E. Fisher

The paper shows MITF promotes melanoma survival by increasing resistance to reactive oxygen species through regulating antioxidant genes like IDH1 and NNT.

24 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky