Systems BiologyCell SystemsPeer-reviewed
δ-α cell-to-cell interactions modulate pancreatic islet Ca2+ oscillation modes
Huixia Ren, Yanjun Li, Beichen Xie…·Chao Tang
The paper shows that δ-cell interactions modulate pancreatic islet Ca2+ oscillation patterns through somatostatin secretion and pharmacological/optogenetic perturbations, revealing a Hopf bifurcation mechanism.
DOI 10.1016/j.cels.2026.101587