Jun Chu

ClearGel enables chronic, near-millimeter two-photon imaging through the intact skull in live mice with high resolution and reversibility.

The paper introduces two red-emitting genetically encoded voltage indicators (GEVIs) that improve sensitivity, brightness, and photostability for imaging action potentials in brain slices and pancreatic islets.

The paper introduces an all-optical technique for brain-wide calcium imaging and optogenetic stimulation in larval zebrafish, showing it can trigger behavior and neural activity changes.

The paper shows that serotonin signaling modulates the coincidence time window in Drosophila associative learning by a feedback circuit involving ACh and 5-HT.

This paper develops a new genetically encoded fluorescent cAMP indicator, G-Flamp1, which shows high sensitivity, brightness, and fast response kinetics for in vivo cAMP imaging.

This paper introduces a gradient two-photon microscopy technique that enables rapid volumetric imaging with reduced phototoxicity by using two axially gradient excitation beams.