Masaki Sasai

This study proposes a molecular clockwork hypothesis for circadian oscillations in KaiABC proteins and develops a theoretical model to test it.

This study shows cohesin maintains condensed euchromatic domains in human cells by preventing local mixing, which is crucial for transcriptional insulation.

This study shows that linker histone H1 acts as a liquid-like glue in chromatin domains, enabling dynamic interactions that support DNA transactions in human cells.

This study develops a genome dynamics model that incorporates mitotic and cell cycle memory to explain chromosome organization across successive cell cycles.

The paper uses OI-DIC imaging to show that a transient increase in depletion force, caused by macromolecular crowding, contributes to mitotic chromosome condensation in human cells.