Shiori Iida

The paper measures local nucleosome motion in living human cells during interphase and finds it remains nearly constant, with changes observed under specific perturbations.

This study shows cohesin maintains condensed euchromatic domains in human cells by preventing local mixing, which is crucial for transcriptional insulation.

The paper uses OI-DIC imaging to show that a transient increase in depletion force, caused by macromolecular crowding, contributes to mitotic chromosome condensation in human cells.