Winnie Lei

The immune response to human primary cholangiocyte organoids is ameliorated by donor-recipient HLA matching.

This paper develops a multimodal therapy for CML combining computational target analysis with nanoparticle-based drug delivery and validates its efficacy in mouse models.

This study generates HLA-edited cholangiocyte organoids with reduced immunogenicity and reports their mutation profiles and immune response in vitro and in vivo.