Mehran Kardar A

The paper investigates how active RNA synthesis influences nuclear condensate patterning by studying nucleolar fibrillar centers and shows that RNA synthesis affects their size, number, and spacing.

This paper develops two models to explain LAT condensate formation in reconstitution experiments, showing that condensate morphologies arise from common dynamics modulated by experimental conditions.

The paper shows that persistent infections increase the likelihood of autoimmune T cell activation by exceeding a quorum threshold through molecular mimicry.