Author

Júlio Souza dos-Santos

Universidade Federal do Rio de JaneiroORCID 0000-0002-1165-4232Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Alessandra Marcia da Fonseca-MartinsiD· 2 shared Daniel Cláudio Oliveira GomesiD· 2 shared Herbert Leonel de Matos GuedesiD· 2 shared Alda Maria Da‐CruziD· 1 shared Alisson Amaral Da-Rocha· 1 shared Antônio José da Silva-GonçalvesiD· 1 shared Bruno Silva‐SantosiD· 1 shared Diogo Oliveira-MacieliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Alessandra Marcia da Fonseca-MartinsORCID

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2 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedAug 4, 2025

Mice Mucosal Leishmaniasis model shown high parasite load, increased cytotoxicity and impaired IL-10+ cells response

Alisson Amaral Da-Rocha, Júlio Souza dos-Santos, Igor Santos Bittencourt…·Herbert Leonel de Matos Guedes

This study evaluates the immunopathological effects of Leishmania amazonensis infection in BALB/c mice via mucosal and dermal routes, finding higher parasite load and inflammation in the mucosa.

1 citation

mouseexperimental assay

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ImmunologyJournal of Leukocyte BiologyPeer-reviewedDec 3, 2024

IL-17A/IFN-γ producing γ δ T cell functional dichotomy impacts cutaneous leishmaniasis in mice

Júlio Souza dos-Santos, Luan Firmino-Cruz, Diogo Oliveira-Maciel…·Herbert Leonel de Matos Guedes

This study shows that IL-17A-producing γδ T cells drive pathogenesis while IFN-γ-producing γδ T cells have therapeutic potential in cutaneous leishmaniasis.

8 citations

mouseexperimental assay

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