Herbert Leonel de Matos Guedes

This study shows that adipose-derived mesenchymal stem cell extracellular vesicles reduce cutaneous leishmaniasis severity through IL-10-dependent immunomodulation without affecting parasite load.

This study investigates nociceptive changes in cutaneous leishmaniasis using C57BL/6 mice, finding IL-1β contributes to thermal hypersensitivity while structural changes cause mechanical desensitization.

This study evaluates the immunopathological effects of Leishmania amazonensis infection in BALB/c mice via mucosal and dermal routes, finding higher parasite load and inflammation in the mucosa.

This study shows that IL-17A-producing γδ T cells drive pathogenesis while IFN-γ-producing γδ T cells have therapeutic potential in cutaneous leishmaniasis.