Vivian Gama

This study shows that MCL-1 inhibition disrupts mitochondrial structure and fatty acid oxidation, leading to depletion of neural progenitor cells.

This study models PEX11β deficiency in human neurogenesis by generating knockout iPSCs, revealing altered peroxisomal morphology, lipid metabolism, and neural progenitor characteristics.

This study shows MCL-1 is essential for oligodendrocyte development by regulating mitochondrial changes and fatty acid β-oxidation in human progenitor cells.

The paper develops a co-culture model of human iPSC-derived neural organoids fused with mouse leptomeninges to study meninges-brain signaling and assesses its stability and utility.

This study shows that oligodendrocytes require MCL-1 to prevent apoptosis and white matter degeneration, suggesting MCL-1 deficiency contributes to leukodystrophy.