Developmental BiologybioRxivPreprint
Sympathetic Nerve Activity Promotes Cardiomyocyte Cell-Cycle Arrest And Binucleation
Li Chen, Alexander Y. Payumo, Kentaro Hirose…·Guo N. Huang
This study shows that sympathetic nerve activity reduces cardiomyocyte proliferation and causes binucleation, which may limit heart regeneration in adults.
DOI 10.1101/124347