Guo N. Huang

This study identifies Rpl3l as a muscle-specific ribosomal protein that regulates chromatin insulation in atrial cardiomyocytes, linking genome structure to cardiac rhythm stability.

This study investigates adaptive right ventricular development in congenital heart disease-associated pulmonary arterial hypertension, finding preserved microvascular density and increased cardiomyocyte hyperplasia support RV function.

This study uses digital holographic imaging to show that mononucleated cardiomyocytes retain proliferative potential while binucleated cells have limited capacity to divide, with size thresholds affecting division ability.

This study identifies factors that reactivate cell cycle activity in adult mouse cardiomyocytes, revealing a functional interaction between E2f2 and Bex1/Tceal8 proteins.

This study shows that loss of Coq10a, a muscle-enriched mitochondrial protein, enhances postnatal cardiac hypertrophy without impairing cardiac function.

The paper investigates the roles of glucocorticoid and vitamin D receptors in cardiomyocyte proliferation, finding that while they inhibit proliferation in vitro, they are not essential for cell-cycle exit in vivo.

This study shows that sympathetic nerve activity reduces cardiomyocyte proliferation and causes binucleation, which may limit heart regeneration in adults.