Author

Mason D. Schmidt

Washington University in St. LouisORCID 0000-0002-1303-9911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Jeffrey R. MillmaniD· 2 shared Punn AugsornworawatiD· 2 shared Matthew IshahakiD· 1 shared Mira Shunkarova· 1 shared Nathaniel J. HogrebeiD· 1 shared Sarah E. GaleiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

Jeffrey R. MillmanORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedApr 2, 2026

Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation

Nathaniel J. Hogrebe, Mason D. Schmidt, Punn Augsornworawat…·Jeffrey R. Millman

The paper shows that depolymerizing F-actin with latrunculin A during early differentiation improves hPSC-derived islet maturation and function by altering signaling pathways and lineage specification.

5 citationstop 3%

humanbulk RNA-seq

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Cell BiologyBMC GenomicsPeer-reviewedJan 24, 2024

Comparative and Integrative Single Cell Analysis Reveals New Insights into the Transcriptional Immaturity of Stem Cell-Derived β Cells

Mason D. Schmidt, Matthew Ishahak, Punn Augsornworawat, Jeffrey R. Millman

This study compares SC-β cells with fetal and adult β cells using single-cell sequencing, finding they share a core β-cell identity but have unique transcriptional profiles with neural-biased gene networks.

30 citationstop 2%

humanscRNA-seq

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