Dino A. Giussani

This study investigates the role of hepatic HIF2α in MASLD, finding that its deletion leads to extra-hepatic complications like cardiac dysfunction and lean mass loss without protecting against liver disease progression.

This study shows that fetal hypoxia increases susceptibility to ventricular arrhythmias in adult offspring by altering excitation-contraction coupling.

This study develops an ovine model of maternal diet-induced obesity during pregnancy and finds fetal sex-specific changes in uterine vascular function.

This study identifies gene expression changes in the carotid body transcriptome across developmental stages in sheep, correlating with the maturation of oxygen chemosensitivity.

This study evaluates the male ovine mammary gland microenvironment, comparing intact and neutered males, and demonstrates its utility as a model for male breast biology.