Mark N. Wu

The paper identifies an extra-SCN brain oscillator in the lateral amygdala that coordinates cellular and behavioral rhythms through mWAKE/ANKFN1 expression.

This study identifies E1 neurons in Drosophila that regulate the transition from arousal to sleep at dusk through light-dependent mechanisms.

FlyVISTA is a machine learning platform that identifies sleep-associated microbehaviors in Drosophila by analyzing high-resolution video data and annotating body parts.

The paper shows that astroglial calcium signaling in Drosophila increases with sleep need and is required for homeostatic sleep rebound, identifying TyrRII as a key receptor involved in this process.

The paper characterizes mWake expression in the adult mouse brain, identifying its presence in neurons and non-neuronal cells across multiple brain regions and providing single-cell RNA sequencing analysis of hypothalamic mWake+ cells.

This study identifies a conserved clock-regulated neural network in mice and Drosophila that controls arousal and sleep, showing that mWake+ cells are critical for circadian-dependent neural excitability.

The paper identifies a circadian pathway in Drosophila where morning and evening oscillators drive pre-motor centers via specific dopaminergic neurons, resulting in a two-peak locomotor activity pattern.