Rohan Chippalkatti

This study shows K-Ras4B sustains ciliation during muscle cell differentiation by localizing to the primary cilium, affecting asymmetric cell divisions and differentiation outcomes.

This study investigates how KRAS regulates de- and re-ciliation in muscle stem- and progenitor cells through interactions with CEP55, Aurora kinase A, and the PDE6D trafficking pathway.

This study develops a genetically encoded PDE6D inhibitor, SNAP-STI, which shows higher potency than small molecule inhibitors but does not effectively inhibit K-Ras membrane anchorage or MAPK signaling.

This study investigates how RAS isoform mutations affect cell differentiation using C2C12 myoblasts, finding distinct roles for K-Ras, N-Ras, and H-Ras and differential effects of pathway drugs.