Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome
Suchira Gallage, Elaine E. Irvine, Jose Efren Barragan Avila…·Dominic J. Withers
This study shows that S6K1 deletion reduces inflammation and immune infiltration in aged livers, suggesting it suppresses the inflammatory SASP, contributing to healthspan benefits.