Author

Sibongiseni KL Poswayo

University of Cape TownORCID 0000-0002-1532-7124Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Organism:human· 1

Frequent Co-Authors

Suraj P. ParihariD· 3 shared Abhimanyu AbhimanyuiD· 1 shared Anca Flavia SavulescuiD· 1 shared Anil Kumar OjhaiD· 1 shared Bibhuti Bhusan MishraiD· 1 shared C. Ronald KahniD· 1 shared Du Toit LootsiD· 1 shared Frank BrombacheriD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Suraj P. PariharORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 15, 2025

Metabolomics of a Cysteinyl Leukotriene Receptor 1 (CysLTR1) Knockout Mouse Model by Analysis of Bronchoalveolar Lavage Fluid Using Gas Chromatography-time of Flight Mass Spectrometry.

Wilson Bamise Adeosun, Sibongiseni KL Poswayo, Suraj P. Parihar, Du Toit Loots

This study examines the metabolic changes in CysLTR1 knockout mice using metabolomics of BALF, revealing disruptions in glucose, lipid, and microbial metabolism.

DOI 10.1101/2025.08.15.670145

mousemetabolomics

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 19, 2025

Protein Kinase C δ: a critical hub regulating macrophage immunomodulatory functions during Mycobacterium tuberculosis infection

Rudranil Hazra, Mumin Ozturk, Nashied Peton…·Suraj P. Parihar

This study investigates the role of PKCδ in macrophage immunomodulation during Mtb infection, finding that its deficiency leads to increased Mtb burden and exacerbated pathology.

DOI 10.1101/2025.05.19.653976

mouseexperimental assay

𝕏 PostBluesky

ImmunologyPLoS PathogensPeer-reviewedOct 4, 2024

Fatty acid metabolism in neutrophils promotes lung damage and bacterial replication during tuberculosis.

Poornima Sankar, Ramon Bossardi Ramos, Jamie H. Corro…·Bibhuti Bhusan Mishra

This study shows that fatty acid metabolism in neutrophils worsens lung damage and bacterial replication in tuberculosis by promoting inflammation and neutrophil recruitment.

37 citationstop 1%

mousehuman

𝕏 PostBluesky