Suraj P. Parihar

This study evaluates the C3HeB/FeJ Kramnik mouse model for TB research by testing a novel Pheroid(R) formulation and highlights limitations in macrophage pathology and B-cell activity.

This study examines the metabolic changes in CysLTR1 knockout mice using metabolomics of BALF, revealing disruptions in glucose, lipid, and microbial metabolism.

This study investigates the role of PKCδ in macrophage immunomodulation during Mtb infection, finding that its deficiency leads to increased Mtb burden and exacerbated pathology.

This study shows that targeting ALOX5/LTA4H signaling reduces TB-induced lung damage and improves bactericidal activity through macrophage-driven inflammation.

This study shows that fatty acid metabolism in neutrophils worsens lung damage and bacterial replication in tuberculosis by promoting inflammation and neutrophil recruitment.

This study shows HIV-1 evades apoptosis in macrophages by manipulating the MAP2K1/ERK2 pathway to dysregulate lincRNA-p21, and suggests MAP2K1/ERK2 inhibitors as a therapeutic strategy.