Kendra K. Frederick

This study uses DNP-assisted NMR to show that α-synuclein adopts helical-rich conformations near the cell periphery in intact cells.

This study shows that the conformational behavior of α-synuclein's disordered amino terminus varies depending on its structural context and environmental conditions.

This study evaluates AsymPolPOK's stability and performance as a polarization agent in mammalian cells, showing its effectiveness with electroporation but limitations due to rapid reduction in the cellular environment.

This study shows that intact cells selectively amplify and remodel amyloid fibrils of α-synuclein, unlike in vitro or lysate systems.