Sakshi Krishna

This study uses DNP-assisted NMR to show that α-synuclein adopts helical-rich conformations near the cell periphery in intact cells.

This study shows that the conformational behavior of α-synuclein's disordered amino terminus varies depending on its structural context and environmental conditions.

This study shows that intact cells selectively amplify and remodel amyloid fibrils of α-synuclein, unlike in vitro or lysate systems.