Author

Rupam Ghosh

The University of Texas Southwestern Medical CenterORCID 0000-0002-3095-621XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Dominique LagascaiD· 2 shared Kendra K. FrederickiD· 2 shared Yiling XiaoiD· 2 shared Jaka KrageljiD· 1 shared Rania DumariehiD· 1 shared Sakshi KrishnaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

Dominique LagascaORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedJun 4, 2025

Spatially resolved DNP-assisted NMR illuminates the conformational ensemble of α-synuclein in intact viable cells.

Jaka Kragelj, Rupam Ghosh, Yiling Xiao…·Kendra K. Frederick

This study uses DNP-assisted NMR to show that α-synuclein adopts helical-rich conformations near the cell periphery in intact cells.

11 citations

experimental assayprotein folding & dynamics

𝕏 PostBluesky

BiophysicsJournal of Magnetic ResonancePeer-reviewedNov 11, 2024

Stability of the polarization agent AsymPolPOK in intact and lysed mammalian cells

Dominique Lagasca, Rupam Ghosh, Yiling Xiao, Kendra K. Frederick

This study evaluates AsymPolPOK's stability and performance as a polarization agent in mammalian cells, showing its effectiveness with electroporation but limitations due to rapid reduction in the cellular environment.

5 citations

humanproteomics

𝕏 PostBluesky