NeurosciencebioRxivPreprint
mTOR driven gene transcription is required for cholesterol production in neurons of the developing cerebral cortex
Martin Schüle, Tamer Butto, Sri Dewi…·Jennifer Winter
This study identifies mTORC1 as a transcriptional regulator of cholesterol biosynthesis genes in developing neurons, linking mTOR activity to cholesterol production and neurodevelopmental disorders.
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