Kaylene M. Young

This study shows that myelin maintenance in adult mice affects synaptic plasticity and neuron homeostasis, while new myelin stabilizes synapses in basal dendrites.

This study shows that pericyte ablation in adult mice leads to blood-brain barrier leakage, gliosis, and behavioral changes such as reduced movement and impaired balance.

This study shows that low intensity repetitive transcranial magnetic stimulation (LI-rTMS) enhances remyelination by increasing myelin production from new and surviving oligodendrocytes in a mouse model of demyelination.

This study compares iPSC-derived pericytes to primary human brain vascular pericytes, showing they express pericyte markers and respond to growth factors and vasoactive mediators, though with gene expression differences.

The paper shows that mature myelin in adult mice is plastic and can modify node of Ranvier length and periaxonal space size to adjust action potential conduction velocity and synchronicity.

This study shows that LRP1 inhibits OPC differentiation in adult mouse brains, and its deletion increases myelination and remyelination.