Nup98 regulates the G1/S transition
Evi M. Malagise, Anna Sherman, Maya Capelson, Jared T. Nordman
The paper shows Nup98 regulates the G1/S transition in Drosophila by promoting S phase entry, with a dominant-negative effect when overexpressed.
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San Diego State UniversityORCID 0000-0002-1695-316XUnclaimed ORCID profile · follow to get notified of new preprints
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5 papers
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Evi M. Malagise, Anna Sherman, Maya Capelson, Jared T. Nordman
The paper shows Nup98 regulates the G1/S transition in Drosophila by promoting S phase entry, with a dominant-negative effect when overexpressed.
Michael O’Sullivan, Julia Hartmann, Maya McLellan…·Maya Capelson
The paper identifies a tumor-promoting role of Nup93-2 in Drosophila, showing its specific effect on gene silencing and JAK/STAT signaling through Polycomb domains.
Shruti Venkat, Tram Nguyen, Cecilia Blangini…·Prashanth Rangan
The paper identifies a developmentally programmed nuclear pore complex (NPC) turnover pathway during oocyte specification in Drosophila, showing that NPC renewal is essential for proper oocyte identity and maternal provisioning.
Chiara Merigliano, Taehyun Ryu, Jakub Cibulka…·Irene Chiolo
The paper shows that Nup98 nucleoporins use phase separation to mobilize heterochromatic repair sites and exclude Rad51, promoting homologous recombination and genome integrity.
Pau Pascual‐García, Shawn C. Little, Maya Capelson
The paper shows that Nup98 stabilizes the transition to a transcriptional memory state in Drosophila cells, independent of initial transcription.