Jared T. Nordman

The paper shows Nup98 regulates the G1/S transition in Drosophila by promoting S phase entry, with a dominant-negative effect when overexpressed.

This study shows NASP prevents H3 aggregation in the cytoplasm, indirectly protecting H3 from degradation during early Drosophila embryogenesis.

The paper uses nanopore sequencing and DNAscent to measure replication fork progression and origin/termination sites in Drosophila, revealing non-uniform fork speeds and variable origin positions.

This study shows BRWD3 promotes KDM5 degradation, which maintains H3K4 methylation levels by balancing H3K4me1 and H3K4me3.

This study identifies NASP as the critical H3-H4 histone chaperone in the Drosophila embryo, showing that its absence leads to degradation of soluble H3-H4 pools and embryonic defects.

The paper shows that nucleoporins, specifically Elys, are required for ORC2 loading onto chromatin and proper replication initiation in Drosophila.

The paper maps and characterizes R-loops during Drosophila embryogenesis, showing developmental plasticity in their abundance and localization without changes in transcriptional program.

The paper shows Rif1 promotes underreplication in Drosophila polyploid cells through both upstream and downstream roles relative to SUUR in controlling replication timing.

This study shows that cell lineage primarily determines replication timing, while Rif1, through its PP1-binding motif, fine-tunes RT in a tissue-specific manner in Drosophila.

The paper identifies Rif1 as a regulator of replication fork progression in Drosophila, acting downstream of SUUR to inhibit fork progression and control DNA copy number.