Owen P. McGuinness

This paper develops and validates a mass spectrometry-based method to measure insulin-stimulated tissue-specific glucose clearance in mice without radiolabels or catheters.

This study shows that Parvin in skeletal muscle is essential for insulin-stimulated glucose uptake and mitochondrial function, while having little effect on liver insulin sensitivity.

This study shows that thermoneutral temperature reduces energy expenditure and insulin-mediated glucose fluxes in mice, while insulin-independent glucose uptake in brown fat adjusts to temperature changes without compromising glucose homeostasis.