Charles J. Buchanan

This paper uses deep neural networks to reconstruct 2D NMR spectra from single-pulse experiments, eliminating transfer delays and enabling high-quality methyl correlation maps for large proteins.

This study presents the first molecular structure of methylthio-alkane reductase, revealing metalloclusters that inform its function and evolutionary relationship to nitrogenases.

Seedless calculates NMR pulses on-the-fly to improve signal-to-noise by compensating for RF inhomogeneity and chemical shift effects.

This study investigates how penicillin G forms immunogenic adducts on proteins and elicits specific antibody responses in mice, revealing clonal dominance and limited cross-reactivity with other beta-lactam antibiotics.