Andrew L. Lovering

This study identifies Rehh as a widespread bacterial toxin with DNase activity, revealing its evolutionary divergence and mechanism of neutralization by immunity proteins.

This study identifies AnkA as a bacterial effector that directly targets the WAVE Regulatory Complex and actin cytoskeleton, using molecular mimicry to subvert host cell functions during infection.

The paper identifies a type VII-secreted toxin in mycobacteria that enables inter-bacterial competition by targeting arabinogalactan.

This study identifies Bd0967 as a C-terminal processing protease in Bdellovibrio bacteriovorus that degrades flagellins and regulates developmental progression.

This paper characterizes TipA and TipB, two proteins from Bdellovibrio bacteriovorus, showing TipA's lipid-binding structure and TipB's role in inducing conformational changes in TipA.

This paper characterizes a PNGaseA enzyme from Bifidobacterium bifidum that preferentially strips N-glycans from peptides over proteins, revealing its structural basis for substrate specificity.

This study identifies LamH, a glycoside hydrolase that cleaves -1,6-mannoside linkages in LAM/LM, enabling their export to the capsule and promoting bacterial growth.

The paper identifies 1-3 peptidoglycan cross-links in Gluconobacter oxydans using modified PGFinder software and discovers an L,D-transpeptidase with a YkuD-related domain responsible for these cross-links.

This study shows that CobB and PRPP synthase form a complex that regulates protein acetylation and deacetylation in E. coli, impacting metabolism and cellular pathways.