Canan Bayraktar

DDRKOL identifies essential DDR genes in glioblastoma using CRISPR screens, revealing four high-confidence candidates validated across multiple assays and models.

This paper develops EGFRvIII-targeted virus-like particles (VLPs) that enable selective genome editing and elimination of glioblastoma cells while sparing non-target cells.

This paper develops ACE2-coated virus-like particles (ACE2-VLPs) that effectively neutralize SARS-CoV-2, including variants, and show superior efficacy compared to ACE2-expressing extracellular vesicles.

The paper develops multimeric sACE2 decoys using SunTag or MoonTag systems, showing >100-fold increased SARS-CoV-2 neutralization compared to monomeric sACE2.