W. Brent Derry

This study identifies GALE as a key regulator of glycoproteome remodelling in RAS-driven cancer, showing its role in sialylation and tumorigenicity.

This study identifies a stress-dependent role for the CPA factor CFIM-1 in maintaining germline integrity in C. elegans by regulating transcript isoform abundance.

This study shows that CDK-4 in C. elegans regulates nucleolar size and metabolism, leading to improved early life thermotolerance but reduced longevity.

This study identifies MRCK-1 and MLC-4 as essential for excretory canal outgrowth in C. elegans, revealing a conserved mechanism for tube development.

This study identifies functional relationships between TSC22D, WNK, and NRBP gene families in macromolecular crowding sensing and cell volume regulation across metazoans.

The paper develops an efficient method for generating long single-stranded DNA donors for CRISPR/Cas9 in C. elegans, enabling large insertions with high efficiency.