Verena Jantsch

This study shows that CIP2A tetramerization is essential for mitotic DNA repair and survival of BRCA1/2 mutant cancer cells.

This study shows ZHP-2/HEI10 regulates CO formation in C. elegans by disassembling proCO factors and recruiting Polo kinase to trigger coarsening and crossover execution.

This study identifies RIPR-1 as a novel BRC-2/BRCA2 interactor that regulates RAD-51 recruitment during meiotic homologous recombination, revealing BRCA2-independent pathways and stage-dependent constraints on DNA repair.

This paper introduces DIA-QCLMS, a framework for quantitative crosslinking mass spectrometry that improves confidence assessment and integrates structural features, showing improved reproducibility in analyzing protein dynamics.

This study identifies a DDK/CDK-12/DNA-2 signaling axis that promotes meiotic DNA end resection in C. elegans, preventing aberrant recombination outcomes.

This study identifies BRA-2 and HIM-17 as distinct factors involved in meiotic synapsis licensing and homolog pairing in C. elegans.

This study identifies PARG's role in promoting meiotic DNA break formation and repair in C. elegans, independent of its catalytic activity.

This study investigates the localization and function of the BRCA1-BARD1 complex during Caenorhabditis elegans meiosis, showing its association with crossover factors and role in RAD-51 recruitment.