Aleksandra S. Kostina

This paper uses a computational framework to identify FDA-approved drugs that can promote cardiomyocyte proliferation, finding lithium as a potential therapeutic but highlighting congenital risks.

The paper identifies YAP1 as a non-canonical effector of RA signaling essential for atrial lineage commitment in cardiac progenitor cells.

This paper develops a human heart assembloid model that recapitulates cardiac neural crest integration and reveals antidepressant effects on cardiac development.