Author

Stephanie V. Trefry

George Mason UniversityORCID 0000-0002-2039-1825Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

Amy L Cregger· 2 shared Chase A Gonzales· 2 shared Christy N Raney· 2 shared Deborah S Gohegan· 2 shared Farooq NasariD· 2 shared Mayanka AwasthiiD· 2 shared N.E. Ziolkowska· 2 shared Nelson A Martinez· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Amy L Cregger

Mutual co-authors in cluster

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4 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 28, 2026

The Sustained Alteration Of Brain Waves In Cynomolgus Macaques Following Aerosol Infection With Venezuelan Equine Encephalitis Virus Subtype IAB

Sara I. Ruiz, Michael V. Accardi, Franco D. Rossi…·Farooq Nasar

This study tracks physiological and EEG changes in cynomolgus macaques after aerosol VEEV-IAB infection, showing rapid autonomic nervous system disruption and persistent EEG alterations without detectable viral persistence.

DOI 10.64898/2026.08.28.747802

non-human primateelectrophysiology

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MicrobiologyJournal of VirologyPeer-reviewedJul 15, 2026

Monkeypox Virus Clade IIb Isolate Exhibits Reduced Virulence Relative to Clade IIa Isolates in Multiple Murine Models

Stephanie V. Trefry, Santiago Vidal-Freire, Mayanka Awasthi…·Farooq Nasar

This study compares the virulence of MPXV clade IIa and IIb isolates in multiple murine models, finding IIb is significantly less virulent with lower lethality.

DOI 10.1128/jvi.00247-26

mouseexperimental assay

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Cell BiologybioRxivPreprintApr 23, 2026

Computational and Proteomic Analyses Reveal Cardiac Dysfunction and Heart Failure-Associated Biomarker Secretion from Venezuelan Equine Encephalitis Virus TC83-infected human IPSC-derived Cardiomyocytes

Stephanie V. Trefry, Layan Wahdan, Tyler DiGangi…·Elsa Ronzier

This study investigates VEEV TC-83 infection's impact on hIPSC-derived cardiomyocytes, revealing cardiac dysfunction and heart failure biomarker secretion.

DOI 10.64898/2026.04.22.720215

humanproteomics

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MicrobiologymSpherePeer-reviewedNov 13, 2024

Recombinant chimeric Horsepox Virus (TNX-801) is attenuated relative to Vaccinia Virus Strains in Human Primary Cell Lines and in Immunocompromised Mice

Stephanie V. Trefry, Mayanka Awasthi, Christy N Raney…·Farooq Nasar

This study compares the attenuation of TNX-801, a recombinant chimeric Horsepox virus, to VACV-based vaccines in cell lines and mice, showing TNX-801 is significantly more attenuated.

3 citations

humanmouse

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